The Joint Worldwide Osteoporosis Basis (IOF) Working Group and the Worldwide Federation of Medical Chemistry (IFCC) Committee on Bone Metabolism have revealed necessary up to date tips for the right use of biochemical indices of bone standing. The place paper marks a major development in bone well being diagnostics and addresses longstanding challenges in analysis attributable to inconsistent terminology, which has hindered information sharing, standardization, and collaborative progress.
The newly proposed time period, “Bone Standing Indices” (BSIs), presents a complete framework to unify terminology and enhance comparability throughout research. Not like beforehand used phrases comparable to “bone turnover markers” or “metabolic markers of bone turnover,” which concentrate on remoted elements of bone metabolism, BSIs present a holistic illustration of bone standing and combine a wider array of factors-including structural parts, metabolic byproducts, enzymes, and regulatory molecules.
Professor Etienne Cavalier, Chair of the Joint IOF Working Group and IFCC Committee on Bone Metabolism, and Vice-Chair of the IOF Committee of Scientific Advisors, emphasised the transformative potential of the brand new standardized nomenclature:
“By adopting this unified nomenclature, researchers and clinicians can improve communication, foster collaboration, make sure the correct interpretation of findings and guarantee constant reporting. This step is important for attaining a unified and complete method to bone standing analysis, benefiting sufferers and advancing the sphere of bone metabolism.”
Within the latest Editorial ‘Standardization of the nomenclature of bone standing indices: a milestone in diagnostic consistency and readability’, the authors urge all stakeholders to undertake the nomenclature persistently of their medical practices and in revealed analysis and suggestions.
This place assertion, collectively endorsed by the IOF and IFCC, represents the end result of excellent collaboration between specialists from each organizations. We imagine the standardized nomenclature will play a pivotal position in advancing the sphere and hope it’s broadly embraced by all stakeholders. By unifying medical language and laboratory reporting, we’ve got the chance to considerably improve affected person care and elevate the standard of bone well being analysis worldwide.”
Professor Nicholas Harvey, co-author and President of the IOF
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Journal reference:
Lombardi, G., et al. (2024). Tips for the right use of the nomenclature of biochemical indices of bone standing: a place assertion of the Joint IOF Working Group and IFCC Committee on Bone Metabolism. Medical Chemistry and Laboratory Medication (CCLM). doi.org/10.1515/cclm-2024-1148.